The protein carriers of hundreds of lipids have been identified
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- RESEARCH BRIEFINGS
- 25 February 2026
The protein carriers of hundreds of lipids have been identified
Different types of lipid molecule are transported around the cell by lipid-transfer proteins. Biochemical approaches have been adapted to measure which lipids are captured by the more than 130 known human lipid-transfer proteins, providing a valuable resource that reveals some principles of how these transporters work.
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This is a summary of: Titeca, K. et al. Systematic analyses of lipid mobilization by human lipid transfer proteins. Nature https://doi.org/10.1038/s41586-025-10040-y (2026).
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doi: https://doi.org/10.1038/d41586-026-00570-4
‘Expert opinion’ and the figure are published under a CC BY 4.0 licence.
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Read the paper: Systematic analyses of lipid mobilization by human lipid transfer proteins
A protein tunnel that shuttles lipids around the cell
Visualizing lipid transport in cells
Subjects
Cell biology
Metabolism
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[Original source](https://www.nature.com/articles/d41586-026-00570-4)